THE HUMAN
ENDOCANNABINOID SYSTEM

The most important physiologic system
for human health.

WHY CANNABIS?

The endogenous cannabinoid system, named after the plant that led to its discovery, is perhaps the most important physiologic system involved in establishing and maintaining human health. Endocannabinoids and their receptors are found throughout the body: in the brain, organs, connective tissues, glands, and immune cells. In each cell and all tissues, the endocannabinoid system performs different tasks, but the goal is always the same; homeostasis, the maintenance of a stable internal environment despite fluctuations in the external environment. There are at least 85 different cannabinoids isolated from cannabis, exhibiting varied effects. Cannabinoids are a class of diverse chemical compounds that act on cannabinoid receptors on cells that repress neurotransmitter release in the brain.
These receptor proteins include the endocannabinoids (produced naturally in the body by humans and animals), and the phytocannabinoids (found in cannabis and some other plants). The most commonly known cannabinoid is the phytocannabinoid 9tetrahydrocannabinol (THC), the primary psychoactive compound of cannabis. Cannabidiol (CBD) is another major constituent of the plant, representing up to 70% in extracts of the plant resin. Accepted delivery methods would include inhalation, digestion, sublingual, topical, and implant application.

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